The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival

NEK2 is a serine/threonine kinase that promotes centrosome splitting and ensures correct chromosome segregation during the G2/M phase of the cell cycle, through phosphorylation of specific substrates. Aberrant expression and activity of NEK2 in cancer cells lead to dysregulation of the centrosome cy...

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Detalles Bibliográficos
Autores principales: Naro, Chiara, Barbagallo, Federica, Chieffi, Paolo, Bourgeois, Cyril F., Paronetto, Maria Paola, Sette, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950702/
https://www.ncbi.nlm.nih.gov/pubmed/24369428
http://dx.doi.org/10.1093/nar/gkt1307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950702/
https://www.ncbi.nlm.nih.gov/pubmed/24369428
http://dx.doi.org/10.1093/nar/gkt1307

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