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The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival

NEK2 is a serine/threonine kinase that promotes centrosome splitting and ensures correct chromosome segregation during the G2/M phase of the cell cycle, through phosphorylation of specific substrates. Aberrant expression and activity of NEK2 in cancer cells lead to dysregulation of the centrosome cy...

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Detalles Bibliográficos
Autores principales:	Naro, Chiara, Barbagallo, Federica, Chieffi, Paolo, Bourgeois, Cyril F., Paronetto, Maria Paola, Sette, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950702/ https://www.ncbi.nlm.nih.gov/pubmed/24369428 http://dx.doi.org/10.1093/nar/gkt1307

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