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Predominance of spliceosomal complex formation over polyadenylation site selection in TDP-43 autoregulation
TDP-43 is a nuclear protein involved in many aspects of RNA metabolism. To ensure cellular viability, its expression levels within cells must be tightly regulated. We have previously demonstrated that TDP-43 autoregulation occurs through the activation of a normally silent intron in its 3′-UTR seque...
Autores principales: | Bembich, Sara, Herzog, Jeremias S., De Conti, Laura, Stuani, Cristiana, Avendaño-Vázquez, S. Eréndira, Buratti, Emanuele, Baralle, Marco, Baralle, Francisco E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950720/ https://www.ncbi.nlm.nih.gov/pubmed/24369426 http://dx.doi.org/10.1093/nar/gkt1343 |
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