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Glandular Odontogenic Cyst: Review of Literature and Report of a New Case with Cytokeratin-19 Expression
The glandular odontogenic cyst (GOC) was a rare jawbone cyst described in 1988 as a distinct entity. This lesion can involve either jaw, and the anterior region of the mandible was the most commonly affected area. Clinical and radiographic findings were not specific, and the diagnosis of GOC can be...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950754/ https://www.ncbi.nlm.nih.gov/pubmed/24624237 http://dx.doi.org/10.2174/1874210601408010001 |
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author | Mascitti, Marco Santarelli, Andrea Sabatucci, Antonio Procaccini, Maurizio Muzio, Lorenzo Lo Zizzi, Antonio Rubini, Corrado |
author_facet | Mascitti, Marco Santarelli, Andrea Sabatucci, Antonio Procaccini, Maurizio Muzio, Lorenzo Lo Zizzi, Antonio Rubini, Corrado |
author_sort | Mascitti, Marco |
collection | PubMed |
description | The glandular odontogenic cyst (GOC) was a rare jawbone cyst described in 1988 as a distinct entity. This lesion can involve either jaw, and the anterior region of the mandible was the most commonly affected area. Clinical and radiographic findings were not specific, and the diagnosis of GOC can be extremely difficult due to the rarity of this lesion. The cyst presented a wall constituted by fibrous connective tissue and was lined by a non-keratinized stratified squamous epithelium of variable thickness. Large areas of the lining epithelium presented cylinder cells, sometimes ciliated. A variable amount of mucina was occasionally noted. Due to the strong similarities, this cyst can be easily misdiag-nosed as a central mucoepidermoid carcinoma (CMEC). Immunohistochemistry may be an aid in diagnosis; in fact has been demonstrated that there were differences in the expression of cytokeratins (CK) in GOC and CMEC. In this study, we reported a new case of GOC in a 38 year female patient. In addition, we carried out a review of 110 previous cases reported in literature. |
format | Online Article Text |
id | pubmed-3950754 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Bentham Open |
record_format | MEDLINE/PubMed |
spelling | pubmed-39507542014-03-12 Glandular Odontogenic Cyst: Review of Literature and Report of a New Case with Cytokeratin-19 Expression Mascitti, Marco Santarelli, Andrea Sabatucci, Antonio Procaccini, Maurizio Muzio, Lorenzo Lo Zizzi, Antonio Rubini, Corrado Open Dent J Article The glandular odontogenic cyst (GOC) was a rare jawbone cyst described in 1988 as a distinct entity. This lesion can involve either jaw, and the anterior region of the mandible was the most commonly affected area. Clinical and radiographic findings were not specific, and the diagnosis of GOC can be extremely difficult due to the rarity of this lesion. The cyst presented a wall constituted by fibrous connective tissue and was lined by a non-keratinized stratified squamous epithelium of variable thickness. Large areas of the lining epithelium presented cylinder cells, sometimes ciliated. A variable amount of mucina was occasionally noted. Due to the strong similarities, this cyst can be easily misdiag-nosed as a central mucoepidermoid carcinoma (CMEC). Immunohistochemistry may be an aid in diagnosis; in fact has been demonstrated that there were differences in the expression of cytokeratins (CK) in GOC and CMEC. In this study, we reported a new case of GOC in a 38 year female patient. In addition, we carried out a review of 110 previous cases reported in literature. Bentham Open 2014-02-07 /pmc/articles/PMC3950754/ /pubmed/24624237 http://dx.doi.org/10.2174/1874210601408010001 Text en © Mascitti et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Mascitti, Marco Santarelli, Andrea Sabatucci, Antonio Procaccini, Maurizio Muzio, Lorenzo Lo Zizzi, Antonio Rubini, Corrado Glandular Odontogenic Cyst: Review of Literature and Report of a New Case with Cytokeratin-19 Expression |
title | Glandular Odontogenic Cyst: Review of Literature and Report of a New Case with Cytokeratin-19 Expression |
title_full | Glandular Odontogenic Cyst: Review of Literature and Report of a New Case with Cytokeratin-19 Expression |
title_fullStr | Glandular Odontogenic Cyst: Review of Literature and Report of a New Case with Cytokeratin-19 Expression |
title_full_unstemmed | Glandular Odontogenic Cyst: Review of Literature and Report of a New Case with Cytokeratin-19 Expression |
title_short | Glandular Odontogenic Cyst: Review of Literature and Report of a New Case with Cytokeratin-19 Expression |
title_sort | glandular odontogenic cyst: review of literature and report of a new case with cytokeratin-19 expression |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950754/ https://www.ncbi.nlm.nih.gov/pubmed/24624237 http://dx.doi.org/10.2174/1874210601408010001 |
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