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Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil
In the present study we surveyed the fauna of phlebotomine sand flies and small mammals in peridomestic areas from a Brazilian municipality where the American cutaneous leishmaniasis (ACL) is endemic. A total of 608 female phlebotomine sand flies were captured during nine months in 2009 and 2010. Se...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950829/ https://www.ncbi.nlm.nih.gov/pubmed/24707492 http://dx.doi.org/10.1155/2014/592986 |
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author | Lara-Silva, Fabiana de Oliveira Barata, Ricardo Andrade Michalsky, Érika Monteiro Ferreira, Eduardo de Castro Lopes, Maria Olímpia Garcia Pinheiro, Aimara da Costa Fortes-Dias, Consuelo Latorre Dias, Edelberto Santos |
author_facet | Lara-Silva, Fabiana de Oliveira Barata, Ricardo Andrade Michalsky, Érika Monteiro Ferreira, Eduardo de Castro Lopes, Maria Olímpia Garcia Pinheiro, Aimara da Costa Fortes-Dias, Consuelo Latorre Dias, Edelberto Santos |
author_sort | Lara-Silva, Fabiana de Oliveira |
collection | PubMed |
description | In the present study we surveyed the fauna of phlebotomine sand flies and small mammals in peridomestic areas from a Brazilian municipality where the American cutaneous leishmaniasis (ACL) is endemic. A total of 608 female phlebotomine sand flies were captured during nine months in 2009 and 2010. Seven different species were represented with 60% of them being Lutzomyia intermedia and Lu. whitmani, both incriminated vectors of ACL. Lu. longipalpis, a proven vector of visceral leishmaniasis (VL) was also captured at high proportion (12.8%). Genomic DNA analysis of 136 species-specific pools of female sand flies followed by molecular genotyping showed the presence of Leishmania infantum DNA in two pools of Lu. longipalpis. The same Leishmania species was found in one blood sample from Rattus norvegicus among 119 blood and tissue samples analysed. This is the first report of Le. infantum in R. norvegicus in the Americas and suggests a possible role for this rodent species in the zoonotic cycle of VL. Our study coincided with the reemergence of VL in Governador Valadares. |
format | Online Article Text |
id | pubmed-3950829 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39508292014-04-06 Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil Lara-Silva, Fabiana de Oliveira Barata, Ricardo Andrade Michalsky, Érika Monteiro Ferreira, Eduardo de Castro Lopes, Maria Olímpia Garcia Pinheiro, Aimara da Costa Fortes-Dias, Consuelo Latorre Dias, Edelberto Santos Biomed Res Int Research Article In the present study we surveyed the fauna of phlebotomine sand flies and small mammals in peridomestic areas from a Brazilian municipality where the American cutaneous leishmaniasis (ACL) is endemic. A total of 608 female phlebotomine sand flies were captured during nine months in 2009 and 2010. Seven different species were represented with 60% of them being Lutzomyia intermedia and Lu. whitmani, both incriminated vectors of ACL. Lu. longipalpis, a proven vector of visceral leishmaniasis (VL) was also captured at high proportion (12.8%). Genomic DNA analysis of 136 species-specific pools of female sand flies followed by molecular genotyping showed the presence of Leishmania infantum DNA in two pools of Lu. longipalpis. The same Leishmania species was found in one blood sample from Rattus norvegicus among 119 blood and tissue samples analysed. This is the first report of Le. infantum in R. norvegicus in the Americas and suggests a possible role for this rodent species in the zoonotic cycle of VL. Our study coincided with the reemergence of VL in Governador Valadares. Hindawi Publishing Corporation 2014 2014-02-23 /pmc/articles/PMC3950829/ /pubmed/24707492 http://dx.doi.org/10.1155/2014/592986 Text en Copyright © 2014 Fabiana de Oliveira Lara-Silva et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lara-Silva, Fabiana de Oliveira Barata, Ricardo Andrade Michalsky, Érika Monteiro Ferreira, Eduardo de Castro Lopes, Maria Olímpia Garcia Pinheiro, Aimara da Costa Fortes-Dias, Consuelo Latorre Dias, Edelberto Santos Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil |
title |
Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil |
title_full |
Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil |
title_fullStr |
Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil |
title_full_unstemmed |
Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil |
title_short |
Rattus norvegicus (Rodentia: Muridae) Infected by Leishmania (Leishmania) infantum (syn. Le. chagasi) in Brazil |
title_sort | rattus norvegicus (rodentia: muridae) infected by leishmania (leishmania) infantum (syn. le. chagasi) in brazil |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950829/ https://www.ncbi.nlm.nih.gov/pubmed/24707492 http://dx.doi.org/10.1155/2014/592986 |
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