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Cardiovascular sequelae in long-term survivors of young peoples' cancer: a linked cohort study

BACKGROUND: We aimed to define the incidence and risk of cardiovascular late effects (LEs) identified from inpatient hospital episode statistics (HES) among long-term survivors of cancer in young people by age at diagnosis (0–14 and 15–29 years). METHODS: Records from the Yorkshire Specialist Regist...

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Autores principales: van Laar, M, Feltbower, R G, Gale, C P, Bowen, D T, Oliver, S E, Glaser, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950874/
https://www.ncbi.nlm.nih.gov/pubmed/24504369
http://dx.doi.org/10.1038/bjc.2014.37
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author van Laar, M
Feltbower, R G
Gale, C P
Bowen, D T
Oliver, S E
Glaser, A
author_facet van Laar, M
Feltbower, R G
Gale, C P
Bowen, D T
Oliver, S E
Glaser, A
author_sort van Laar, M
collection PubMed
description BACKGROUND: We aimed to define the incidence and risk of cardiovascular late effects (LEs) identified from inpatient hospital episode statistics (HES) among long-term survivors of cancer in young people by age at diagnosis (0–14 and 15–29 years). METHODS: Records from the Yorkshire Specialist Register of Cancer in Children and Young People (1991–2006) were linked to inpatient HES data (1996–2011) to assess rates of cardiovascular LEs. Rates were compared with the general population in Yorkshire using age–sex-matched HES records for the entire region. RESULTS: Of 3247 survivors of cancer, 3.6% had at least one cardiovascular LE. Overall, cardiovascular hospitalisations for the childhood cohort were threefold higher compared with the general population, but did not differ for young adults. For young adults, increased rates were limited to pericardial disease, cardiomyopathy and heart failure, pulmonary heart disease, hypertension and conduction disorders. CONCLUSIONS: Survivors of childhood and young adult cancer remain at increased risk of cardiovascular LEs compared with the general population.
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spelling pubmed-39508742015-03-04 Cardiovascular sequelae in long-term survivors of young peoples' cancer: a linked cohort study van Laar, M Feltbower, R G Gale, C P Bowen, D T Oliver, S E Glaser, A Br J Cancer Short Communication BACKGROUND: We aimed to define the incidence and risk of cardiovascular late effects (LEs) identified from inpatient hospital episode statistics (HES) among long-term survivors of cancer in young people by age at diagnosis (0–14 and 15–29 years). METHODS: Records from the Yorkshire Specialist Register of Cancer in Children and Young People (1991–2006) were linked to inpatient HES data (1996–2011) to assess rates of cardiovascular LEs. Rates were compared with the general population in Yorkshire using age–sex-matched HES records for the entire region. RESULTS: Of 3247 survivors of cancer, 3.6% had at least one cardiovascular LE. Overall, cardiovascular hospitalisations for the childhood cohort were threefold higher compared with the general population, but did not differ for young adults. For young adults, increased rates were limited to pericardial disease, cardiomyopathy and heart failure, pulmonary heart disease, hypertension and conduction disorders. CONCLUSIONS: Survivors of childhood and young adult cancer remain at increased risk of cardiovascular LEs compared with the general population. Nature Publishing Group 2014-03-04 2014-02-06 /pmc/articles/PMC3950874/ /pubmed/24504369 http://dx.doi.org/10.1038/bjc.2014.37 Text en Copyright © 2014 Cancer Research UK http://creativecommons.org/licenses/by-nc-sa/3.0/ From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Short Communication
van Laar, M
Feltbower, R G
Gale, C P
Bowen, D T
Oliver, S E
Glaser, A
Cardiovascular sequelae in long-term survivors of young peoples' cancer: a linked cohort study
title Cardiovascular sequelae in long-term survivors of young peoples' cancer: a linked cohort study
title_full Cardiovascular sequelae in long-term survivors of young peoples' cancer: a linked cohort study
title_fullStr Cardiovascular sequelae in long-term survivors of young peoples' cancer: a linked cohort study
title_full_unstemmed Cardiovascular sequelae in long-term survivors of young peoples' cancer: a linked cohort study
title_short Cardiovascular sequelae in long-term survivors of young peoples' cancer: a linked cohort study
title_sort cardiovascular sequelae in long-term survivors of young peoples' cancer: a linked cohort study
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950874/
https://www.ncbi.nlm.nih.gov/pubmed/24504369
http://dx.doi.org/10.1038/bjc.2014.37
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