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Mitochondrial-Targeted Curcuminoids: A Strategy to Enhance Bioavailability and Anticancer Efficacy of Curcumin

Although the anti-cancer effects of curcumin has been shown in various cancer cell types, in vitro, pre-clinical and clinical studies showed only a limited efficacy, even at high doses. This is presumably due to low bioavailability in both plasma and tissues, particularly due to poor intracellular a...

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Detalles Bibliográficos
Autores principales: Reddy, Cheruku Apoorva, Somepalli, Venkateswarlu, Golakoti, Trimurtulu, Kanugula, Anantha KoteswaraRao, Karnewar, Santosh, Rajendiran, Karthikraj, Vasagiri, Nagarjuna, Prabhakar, Sripadi, Kuppusamy, Periannan, Kotamraju, Srigiridhar, Kutala, Vijay Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951186/
https://www.ncbi.nlm.nih.gov/pubmed/24622734
http://dx.doi.org/10.1371/journal.pone.0089351