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Long-Term Implanted cOFM Probe Causes Minimal Tissue Reaction in the Brain
This study investigated the histological tissue reaction to long-term implanted cerebral open flow microperfusion (cOFM) probes in the frontal lobe of the rat brain. Most probe-based cerebral fluid sampling techniques are limited in application time due to the formation of a glial scar that hinders...
Autores principales: | Birngruber, Thomas, Ghosh, Arijit, Hochmeister, Sonja, Asslaber, Martin, Kroath, Thomas, Pieber, Thomas R., Sinner, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951198/ https://www.ncbi.nlm.nih.gov/pubmed/24621608 http://dx.doi.org/10.1371/journal.pone.0090221 |
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