HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells

The n-butanol extract of the roots of Glyphaea brevis was analysed. HPLC analysis suggested the presence of phenolic compounds like protocatechuic acid (PCA). The extract showed moderate cytotoxic activity against C6 glioma cells (EC(50) > 1 mg/ml).

Detalles Bibliográficos
Autores principales: Konan, Koffi Marcel, Mamyrbekova-Bekro, Janat Akhanovna, Bakalara, Norbert, Virieux, David, Pirat, Jean-Luc, Bekro, Yves-Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951227/
https://www.ncbi.nlm.nih.gov/pubmed/24634849
http://dx.doi.org/10.3797/scipharm.1307-08
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author Konan, Koffi Marcel
Mamyrbekova-Bekro, Janat Akhanovna
Bakalara, Norbert
Virieux, David
Pirat, Jean-Luc
Bekro, Yves-Alain
author_facet Konan, Koffi Marcel
Mamyrbekova-Bekro, Janat Akhanovna
Bakalara, Norbert
Virieux, David
Pirat, Jean-Luc
Bekro, Yves-Alain
author_sort Konan, Koffi Marcel
collection PubMed
description The n-butanol extract of the roots of Glyphaea brevis was analysed. HPLC analysis suggested the presence of phenolic compounds like protocatechuic acid (PCA). The extract showed moderate cytotoxic activity against C6 glioma cells (EC(50) > 1 mg/ml).
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spelling pubmed-39512272014-03-14 HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells Konan, Koffi Marcel Mamyrbekova-Bekro, Janat Akhanovna Bakalara, Norbert Virieux, David Pirat, Jean-Luc Bekro, Yves-Alain Sci Pharm Short Communication The n-butanol extract of the roots of Glyphaea brevis was analysed. HPLC analysis suggested the presence of phenolic compounds like protocatechuic acid (PCA). The extract showed moderate cytotoxic activity against C6 glioma cells (EC(50) > 1 mg/ml). Österreichische Apotheker-Verlagsgesellschaft 2014 2013-11-19 /pmc/articles/PMC3951227/ /pubmed/24634849 http://dx.doi.org/10.3797/scipharm.1307-08 Text en © Konan et al.; licensee Österreichische Apotheker-Verlagsgesellschaft m. b. H., Vienna, Austria. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Konan, Koffi Marcel
Mamyrbekova-Bekro, Janat Akhanovna
Bakalara, Norbert
Virieux, David
Pirat, Jean-Luc
Bekro, Yves-Alain
HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells
title HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells
title_full HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells
title_fullStr HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells
title_full_unstemmed HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells
title_short HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells
title_sort hplc analysis and cytotoxicity of n-butanol extract from glyphaea brevis roots against c6 glioma cells
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951227/
https://www.ncbi.nlm.nih.gov/pubmed/24634849
http://dx.doi.org/10.3797/scipharm.1307-08
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