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Side Chain Hydrophobicity Modulates Therapeutic Activity and Membrane Selectivity of Antimicrobial Peptide Mastoparan-X

The discovery of new anti-infective compounds is stagnating and multi-resistant bacteria continue to emerge, threatening to end the “antibiotic era”. Antimicrobial peptides (AMPs) and lipo-peptides such as daptomycin offer themselves as a new potential class of antibiotics; however, further optimiza...

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Detalles Bibliográficos
Autores principales:	Henriksen, Jonas R., Etzerodt, Thomas, Gjetting, Torben, Andresen, Thomas L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951324/ https://www.ncbi.nlm.nih.gov/pubmed/24621994 http://dx.doi.org/10.1371/journal.pone.0091007

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