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Isoproterenol Induces Vascular Oxidative Stress and Endothelial Dysfunction via a Giα-Coupled β(2)-Adrenoceptor Signaling Pathway

OBJECTIVE: Sustained β-adrenergic stimulation is a hallmark of sympathetic hyperactivity in cardiovascular diseases. It is associated with oxidative stress and altered vasoconstrictor tone. This study investigated the β-adrenoceptor subtype and the signaling pathways implicated in the vascular effec...

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Detalles Bibliográficos
Autores principales:	Davel, Ana P., Brum, Patricia C., Rossoni, Luciana V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951496/ https://www.ncbi.nlm.nih.gov/pubmed/24622771 http://dx.doi.org/10.1371/journal.pone.0091877

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