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Deubiquitination and stabilization of PTEN by USP13

The tumor suppressor PTEN is frequently lost in human cancers. In addition to gene mutations and deletions, recent studies have revealed the importance of post-translational modifications, such as ubiquitination, in the regulation of PTEN stability, activity and localization. However, the deubiquiti...

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Detalles Bibliográficos
Autores principales: Zhang, Jinsong, Zhang, Peijing, Wei, Yongkun, Piao, Hai-long, Wang, Wenqi, Maddika, Subbareddy, Wang, Min, Chen, Dahu, Sun, Yutong, Hung, Mien-Chie, Chen, Junjie, Ma, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951854/
https://www.ncbi.nlm.nih.gov/pubmed/24270891
http://dx.doi.org/10.1038/ncb2874

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