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Selective deletion of the endothelial sphingosine-1-phosphate 1 receptor exacerbates kidney ischemia-reperfusion injury

The role for the endothelial sphingosine-1-phosphate 1 receptor (S1P1R) in acute kidney injury (AKI) remains unclear as germline endothelial S1P1R deletion is embryonically lethal. Here, we generated conditional endothelial S1P1R deficiency by crossing mice with floxed S1P1R with mice expressing a t...

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Detalles Bibliográficos
Autores principales:	Ham, Ahrom, Kim, Mihwa, Kim, Joo Yun, Brown, Kevin M., Fruttiger, Marcus, D’Agati, Vivette D., Lee, H. Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952061/ https://www.ncbi.nlm.nih.gov/pubmed/24025642 http://dx.doi.org/10.1038/ki.2013.345

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