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Selective deletion of the endothelial sphingosine-1-phosphate 1 receptor exacerbates kidney ischemia-reperfusion injury

The role for the endothelial sphingosine-1-phosphate 1 receptor (S1P1R) in acute kidney injury (AKI) remains unclear as germline endothelial S1P1R deletion is embryonically lethal. Here, we generated conditional endothelial S1P1R deficiency by crossing mice with floxed S1P1R with mice expressing a t...

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Bibliografische gegevens
Hoofdauteurs: Ham, Ahrom, Kim, Mihwa, Kim, Joo Yun, Brown, Kevin M., Fruttiger, Marcus, D’Agati, Vivette D., Lee, H. Thomas
Formaat: Online Artikel Texto
Taal:English
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952061/
https://www.ncbi.nlm.nih.gov/pubmed/24025642
http://dx.doi.org/10.1038/ki.2013.345