KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9

Epithelial to mesenchymal transition (EMT) and extracellular matrix degradation are critical for the initiation and progression of tumor invasion. We have recently identified Krüppel-like factor 8 (KLF8) as a critical inducer of EMT and invasion. KLF8 induces EMT primarily by repressing E-cadherin t...

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Detalles Bibliográficos
Autores principales: Wang, Xianhui, Lu, Heng, Urvalek, Alison M., Li, Tianshu, Yu, Lin, Lamar, John, DiPersio, C. Michael, Feustel, Paul J., Zhao, Jihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952074/
https://www.ncbi.nlm.nih.gov/pubmed/21151179
http://dx.doi.org/10.1038/onc.2010.563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952074/
https://www.ncbi.nlm.nih.gov/pubmed/21151179
http://dx.doi.org/10.1038/onc.2010.563

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