An aggregate analysis of many predicted structures to reduce errors in protein structure comparison caused by conformational flexibility

BACKGROUND: Conformational flexibility creates errors in the comparison of protein structures. Even small changes in backbone or sidechain conformation can radically alter the shape of ligand binding cavities. These changes can cause structure comparison programs to overlook functionally related pro...

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Detalles Bibliográficos
Autores principales: Godshall, Brian G, Tang, Yisheng, Yang, Wenjie, Chen, Brian Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952246/
https://www.ncbi.nlm.nih.gov/pubmed/24564934
http://dx.doi.org/10.1186/1472-6807-13-S1-S10

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