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Fine Needle Aspiration Cytology in Pediatric Age Group with Special Reference to Pediatric Tumors: A Retrospective Study Evaluating Its Diagnostic Role and Efficacy
BACKGROUND: Fine needle aspiration cytology (FNAC) is a well-established diagnostic technique in adult mass lesions but a comparatively new technique to pediatric lesions. AIM: The current study aims to evaluate the role of FNAC in pediatric age with special reference to pediatric tumors. SUBJECTS A...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952295/ https://www.ncbi.nlm.nih.gov/pubmed/24669329 http://dx.doi.org/10.4103/2141-9248.126608 |
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author | Prathima, S Suresh, TN Harendra Kumar, ML Krishnappa, J |
author_facet | Prathima, S Suresh, TN Harendra Kumar, ML Krishnappa, J |
author_sort | Prathima, S |
collection | PubMed |
description | BACKGROUND: Fine needle aspiration cytology (FNAC) is a well-established diagnostic technique in adult mass lesions but a comparatively new technique to pediatric lesions. AIM: The current study aims to evaluate the role of FNAC in pediatric age with special reference to pediatric tumors. SUBJECTS AND METHODS: A retrospective study of FNAC in children ≤ 18 years of age presenting with mass lesions was studied for 5 years. Distribution of cases in different age groups, sex, and site of lesion was analyzed. Pediatric lesions were categorized into non-neoplastic, benign, and malignant conditions. Diagnostic efficacy was assessed by comparing subsequent histopathological examination wherever possible. STATISTICAL ANALYSIS: Epi info 07 (Centers for Disease Control and Prevention in Atlanta, Georgia (USA) 07) and values were presented as simple percentages. RESULTS: FNAC was performed on 2903 cases in 5 years out of which 327 cases 11.3% (327/2903) were ≤ 18 years of age. Out of 327 cases, 180 cases 55% (180/327) were between 11 and 18 years. Male to female ratio was 1.15:1. The commonest site for FNAC was cervical lymph node swelling 48.3% (158/327). Reactive lymphadenitis was the commonest diagnosis among all mass lesions 38.8% (103/265), whereas Fibroadenoma 20.8% (10/49) was commonest diagnosis among benign lesions and among malignant lesions there were two cases 15.3% (2/13) each of Hodgkins and non-Hodgkins lymphoma and one case of chondrosarcoma. The positive predictive value of diagnosing malignant lesions on FNAC was 100%. CONCLUSIONS: The ease of FNAC along with its high diagnostic accuracy makes it a desirable method for diagnosing lesions in children. |
format | Online Article Text |
id | pubmed-3952295 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-39522952014-03-25 Fine Needle Aspiration Cytology in Pediatric Age Group with Special Reference to Pediatric Tumors: A Retrospective Study Evaluating Its Diagnostic Role and Efficacy Prathima, S Suresh, TN Harendra Kumar, ML Krishnappa, J Ann Med Health Sci Res Original Article BACKGROUND: Fine needle aspiration cytology (FNAC) is a well-established diagnostic technique in adult mass lesions but a comparatively new technique to pediatric lesions. AIM: The current study aims to evaluate the role of FNAC in pediatric age with special reference to pediatric tumors. SUBJECTS AND METHODS: A retrospective study of FNAC in children ≤ 18 years of age presenting with mass lesions was studied for 5 years. Distribution of cases in different age groups, sex, and site of lesion was analyzed. Pediatric lesions were categorized into non-neoplastic, benign, and malignant conditions. Diagnostic efficacy was assessed by comparing subsequent histopathological examination wherever possible. STATISTICAL ANALYSIS: Epi info 07 (Centers for Disease Control and Prevention in Atlanta, Georgia (USA) 07) and values were presented as simple percentages. RESULTS: FNAC was performed on 2903 cases in 5 years out of which 327 cases 11.3% (327/2903) were ≤ 18 years of age. Out of 327 cases, 180 cases 55% (180/327) were between 11 and 18 years. Male to female ratio was 1.15:1. The commonest site for FNAC was cervical lymph node swelling 48.3% (158/327). Reactive lymphadenitis was the commonest diagnosis among all mass lesions 38.8% (103/265), whereas Fibroadenoma 20.8% (10/49) was commonest diagnosis among benign lesions and among malignant lesions there were two cases 15.3% (2/13) each of Hodgkins and non-Hodgkins lymphoma and one case of chondrosarcoma. The positive predictive value of diagnosing malignant lesions on FNAC was 100%. CONCLUSIONS: The ease of FNAC along with its high diagnostic accuracy makes it a desirable method for diagnosing lesions in children. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3952295/ /pubmed/24669329 http://dx.doi.org/10.4103/2141-9248.126608 Text en Copyright: © Annals of Medical and Health Sciences Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Prathima, S Suresh, TN Harendra Kumar, ML Krishnappa, J Fine Needle Aspiration Cytology in Pediatric Age Group with Special Reference to Pediatric Tumors: A Retrospective Study Evaluating Its Diagnostic Role and Efficacy |
title | Fine Needle Aspiration Cytology in Pediatric Age Group with Special Reference to Pediatric Tumors: A Retrospective Study Evaluating Its Diagnostic Role and Efficacy |
title_full | Fine Needle Aspiration Cytology in Pediatric Age Group with Special Reference to Pediatric Tumors: A Retrospective Study Evaluating Its Diagnostic Role and Efficacy |
title_fullStr | Fine Needle Aspiration Cytology in Pediatric Age Group with Special Reference to Pediatric Tumors: A Retrospective Study Evaluating Its Diagnostic Role and Efficacy |
title_full_unstemmed | Fine Needle Aspiration Cytology in Pediatric Age Group with Special Reference to Pediatric Tumors: A Retrospective Study Evaluating Its Diagnostic Role and Efficacy |
title_short | Fine Needle Aspiration Cytology in Pediatric Age Group with Special Reference to Pediatric Tumors: A Retrospective Study Evaluating Its Diagnostic Role and Efficacy |
title_sort | fine needle aspiration cytology in pediatric age group with special reference to pediatric tumors: a retrospective study evaluating its diagnostic role and efficacy |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952295/ https://www.ncbi.nlm.nih.gov/pubmed/24669329 http://dx.doi.org/10.4103/2141-9248.126608 |
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