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A conservation and biophysics guided stochastic approach to refining docked multimeric proteins
BACKGROUND: We introduce a protein docking refinement method that accepts complexes consisting of any number of monomeric units. The method uses a scoring function based on a tight coupling between evolutionary conservation, geometry and physico-chemical interactions. Understanding the role of prote...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952451/ https://www.ncbi.nlm.nih.gov/pubmed/24565106 http://dx.doi.org/10.1186/1472-6807-13-S1-S7 |