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One in a Million: Flow Cytometric Sorting of Single Cell-Lysate Assays in Monodisperse Picolitre Double Emulsion Droplets for Directed Evolution
[Image: see text] Directed evolution relies on iterative cycles of randomization and selection. The outcome of an artificial evolution experiment is crucially dependent on (i) the numbers of variants that can be screened and (ii) the quality of the assessment of each clone that forms the basis for s...
Autores principales: | Zinchenko, Anastasia, Devenish, Sean R. A., Kintses, Balint, Colin, Pierre-Yves, Fischlechner, Martin, Hollfelder, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952496/ https://www.ncbi.nlm.nih.gov/pubmed/24517505 http://dx.doi.org/10.1021/ac403585p |
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