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High Rate of HIV Resuppression After Viral Failure on First-line Antiretroviral Therapy in the Absence of Switch to Second-line Therapy
In a randomized comparison of nevirapine or abacavir with zidovudine plus lamivudine, routine viral load monitoring was not performed, yet 27% of individuals with viral failure at week 48 experienced resuppression by week 96 without switching. This supports World Health Organization recommendations...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952602/ https://www.ncbi.nlm.nih.gov/pubmed/24352348 http://dx.doi.org/10.1093/cid/cit933 |
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author | Gupta, Ravindra K. Goodall, Ruth L. Ranopa, Michael Kityo, Cissy Munderi, Paula Lyagoba, Fred Mugarura, Lincoln Gilks, Charles F. Kaleebu, Pontiano Pillay, Deenan Grosskurth, H. Munderi, P. Kabuye, G. Nsibambi, D. Kasirye, R. Zalwango, E. Nakazibwe, M. Kikaire, B. Nassuna, G. Massa, R. Fadhiru, K. Namyalo, M. Zalwango, A. Generous, L. Khauka, P. Rutikarayo, N. Nakahima, W. Mugisha, A. Todd, J. Levin, J. Muyingo, S. Ruberantwari, A. Kaleebu, P. Yirrell, D. Ndembi, N. Lyagoba, F. Hughes, P. Aber, M. Medina Lara, A. Foster, S. Amurwon, J. Mugyenyi, P. Kityo, C. Ssali, F. Tumukunde, D. Otim, T. Kabanda, J. Musana, H. Akao, J. Kyomugisha, H. Byamukama, A. Sabiiti, J. Komugyena, J. Wavamunno, P. Mukiibi, S. Drasiku, A. Byaruhanga, R. Labeja, O. Katundu, P. Tugume, S. Awio, P. Namazzi, A. Bakeinyaga, T. G. Katabira, H. Abaine, D. Tukamushaba, J. Anywar, W. Ojiambo, W. Angweng, E. Murungi, S. Haguma, W. Atwiine, S. Kigozi, J. Latif, A. Hakim, J. Robertson, V. Reid, A. Chidziva, E. Bulaya-Tembo, R. Musoro, G. Taziwa, F. Chimbetete, C. Chakonza, L. Mawora, A. Muvirimi, C. Tinago, G. Svovanapasis, P. Simango, M. Chirema, O. Machingura, J. Mutsai, S. Phiri, M. Bafana, T. Chirara, M. Muchabaiwa, L. Muzambi, M. Katabira, E. Ronald, A. Kambungu, A. Lutwama, F. Nanfuka, A. Walusimbi, J. Nabankema, E. Nalumenya, R. Namuli, T. Kulume, R. Namata, I. Nyachwo, L. Florence, A. Kusiima, A. Lubwama, E. Nairuba, R. Oketta, F. Buluma, E. Waita, R. Ojiambo, H. Sadik, F. Wanyama, J. Nabongo, P. Ochai, R. Muhweezi, D. Gilks, C. Boocock, K. Puddephatt, C. Winogron, D. Bohannon, J. Darbyshire, J. Gibb, M. D. Burke, A. Bray, D. Babiker, A. Walker, S. A. Wilkes, H. Rauchenberger, M. Sheehan, S. Peto, L. Taylor, K. Spyer, M. Ferrier, A. Naidoo, B. Dunn, D. Goodall, R. Nanfuka, R. Mufuka-Kapuya, C. Kaleebu, P. Pillay, D. Awio, P. Chirara, M. Dunn, D. Gilks, C. Goodall, R. Kapaata, A. Katuramur, M. Lyagoba, F. Magala, R. Magambo, B. Mataruka, K. McCormick, A. Mugarura, L. Musunga, T. Nabankkema, M. Nkalubo, J. Nkurunziza, P. Parry, C. Robertson, V. Spyer, M. Yirrell, D. Medina Lara, A. Foster, S. Amurwon, J. Nyanzi Wakholi, B. Kigozi, J. Muchabaiwa, L. Muzambi, M. Weller, I. Babiker, A. Bahendeka, S. Bassett, M. Chogo Wapakhabulo, A. Darbyshire, J. Gazzard, B. Gilks, C. Hakim, J. Latif, A. Mapuchere, C. Mugurungi, O. Mugyenyi, P. Burke, C. Jones, S. Newland, C. Rahim, S. Rooney, J. Smith, M. Snowden, W. Steens, J.-M. Breckenridge, A. McLaren, A. Hill, C. Matenga, J. Pozniak, A. Serwadda, D. Peto, T. Palfreeman, A. Borok, M. |
author_facet | Gupta, Ravindra K. Goodall, Ruth L. Ranopa, Michael Kityo, Cissy Munderi, Paula Lyagoba, Fred Mugarura, Lincoln Gilks, Charles F. Kaleebu, Pontiano Pillay, Deenan Grosskurth, H. Munderi, P. Kabuye, G. Nsibambi, D. Kasirye, R. Zalwango, E. Nakazibwe, M. Kikaire, B. Nassuna, G. Massa, R. Fadhiru, K. Namyalo, M. Zalwango, A. Generous, L. Khauka, P. Rutikarayo, N. Nakahima, W. Mugisha, A. Todd, J. Levin, J. Muyingo, S. Ruberantwari, A. Kaleebu, P. Yirrell, D. Ndembi, N. Lyagoba, F. Hughes, P. Aber, M. Medina Lara, A. Foster, S. Amurwon, J. Mugyenyi, P. Kityo, C. Ssali, F. Tumukunde, D. Otim, T. Kabanda, J. Musana, H. Akao, J. Kyomugisha, H. Byamukama, A. Sabiiti, J. Komugyena, J. Wavamunno, P. Mukiibi, S. Drasiku, A. Byaruhanga, R. Labeja, O. Katundu, P. Tugume, S. Awio, P. Namazzi, A. Bakeinyaga, T. G. Katabira, H. Abaine, D. Tukamushaba, J. Anywar, W. Ojiambo, W. Angweng, E. Murungi, S. Haguma, W. Atwiine, S. Kigozi, J. Latif, A. Hakim, J. Robertson, V. Reid, A. Chidziva, E. Bulaya-Tembo, R. Musoro, G. Taziwa, F. Chimbetete, C. Chakonza, L. Mawora, A. Muvirimi, C. Tinago, G. Svovanapasis, P. Simango, M. Chirema, O. Machingura, J. Mutsai, S. Phiri, M. Bafana, T. Chirara, M. Muchabaiwa, L. Muzambi, M. Katabira, E. Ronald, A. Kambungu, A. Lutwama, F. Nanfuka, A. Walusimbi, J. Nabankema, E. Nalumenya, R. Namuli, T. Kulume, R. Namata, I. Nyachwo, L. Florence, A. Kusiima, A. Lubwama, E. Nairuba, R. Oketta, F. Buluma, E. Waita, R. Ojiambo, H. Sadik, F. Wanyama, J. Nabongo, P. Ochai, R. Muhweezi, D. Gilks, C. Boocock, K. Puddephatt, C. Winogron, D. Bohannon, J. Darbyshire, J. Gibb, M. D. Burke, A. Bray, D. Babiker, A. Walker, S. A. Wilkes, H. Rauchenberger, M. Sheehan, S. Peto, L. Taylor, K. Spyer, M. Ferrier, A. Naidoo, B. Dunn, D. Goodall, R. Nanfuka, R. Mufuka-Kapuya, C. Kaleebu, P. Pillay, D. Awio, P. Chirara, M. Dunn, D. Gilks, C. Goodall, R. Kapaata, A. Katuramur, M. Lyagoba, F. Magala, R. Magambo, B. Mataruka, K. McCormick, A. Mugarura, L. Musunga, T. Nabankkema, M. Nkalubo, J. Nkurunziza, P. Parry, C. Robertson, V. Spyer, M. Yirrell, D. Medina Lara, A. Foster, S. Amurwon, J. Nyanzi Wakholi, B. Kigozi, J. Muchabaiwa, L. Muzambi, M. Weller, I. Babiker, A. Bahendeka, S. Bassett, M. Chogo Wapakhabulo, A. Darbyshire, J. Gazzard, B. Gilks, C. Hakim, J. Latif, A. Mapuchere, C. Mugurungi, O. Mugyenyi, P. Burke, C. Jones, S. Newland, C. Rahim, S. Rooney, J. Smith, M. Snowden, W. Steens, J.-M. Breckenridge, A. McLaren, A. Hill, C. Matenga, J. Pozniak, A. Serwadda, D. Peto, T. Palfreeman, A. Borok, M. |
author_sort | Gupta, Ravindra K. |
collection | PubMed |
description | In a randomized comparison of nevirapine or abacavir with zidovudine plus lamivudine, routine viral load monitoring was not performed, yet 27% of individuals with viral failure at week 48 experienced resuppression by week 96 without switching. This supports World Health Organization recommendations that suspected viral failure should trigger adherence counseling and repeat measurement before a treatment switch is considered. |
format | Online Article Text |
id | pubmed-3952602 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-39526022014-03-17 High Rate of HIV Resuppression After Viral Failure on First-line Antiretroviral Therapy in the Absence of Switch to Second-line Therapy Gupta, Ravindra K. Goodall, Ruth L. Ranopa, Michael Kityo, Cissy Munderi, Paula Lyagoba, Fred Mugarura, Lincoln Gilks, Charles F. Kaleebu, Pontiano Pillay, Deenan Grosskurth, H. Munderi, P. Kabuye, G. Nsibambi, D. Kasirye, R. Zalwango, E. Nakazibwe, M. Kikaire, B. Nassuna, G. Massa, R. Fadhiru, K. Namyalo, M. Zalwango, A. Generous, L. Khauka, P. Rutikarayo, N. Nakahima, W. Mugisha, A. Todd, J. Levin, J. Muyingo, S. Ruberantwari, A. Kaleebu, P. Yirrell, D. Ndembi, N. Lyagoba, F. Hughes, P. Aber, M. Medina Lara, A. Foster, S. Amurwon, J. Mugyenyi, P. Kityo, C. Ssali, F. Tumukunde, D. Otim, T. Kabanda, J. Musana, H. Akao, J. Kyomugisha, H. Byamukama, A. Sabiiti, J. Komugyena, J. Wavamunno, P. Mukiibi, S. Drasiku, A. Byaruhanga, R. Labeja, O. Katundu, P. Tugume, S. Awio, P. Namazzi, A. Bakeinyaga, T. G. Katabira, H. Abaine, D. Tukamushaba, J. Anywar, W. Ojiambo, W. Angweng, E. Murungi, S. Haguma, W. Atwiine, S. Kigozi, J. Latif, A. Hakim, J. Robertson, V. Reid, A. Chidziva, E. Bulaya-Tembo, R. Musoro, G. Taziwa, F. Chimbetete, C. Chakonza, L. Mawora, A. Muvirimi, C. Tinago, G. Svovanapasis, P. Simango, M. Chirema, O. Machingura, J. Mutsai, S. Phiri, M. Bafana, T. Chirara, M. Muchabaiwa, L. Muzambi, M. Katabira, E. Ronald, A. Kambungu, A. Lutwama, F. Nanfuka, A. Walusimbi, J. Nabankema, E. Nalumenya, R. Namuli, T. Kulume, R. Namata, I. Nyachwo, L. Florence, A. Kusiima, A. Lubwama, E. Nairuba, R. Oketta, F. Buluma, E. Waita, R. Ojiambo, H. Sadik, F. Wanyama, J. Nabongo, P. Ochai, R. Muhweezi, D. Gilks, C. Boocock, K. Puddephatt, C. Winogron, D. Bohannon, J. Darbyshire, J. Gibb, M. D. Burke, A. Bray, D. Babiker, A. Walker, S. A. Wilkes, H. Rauchenberger, M. Sheehan, S. Peto, L. Taylor, K. Spyer, M. Ferrier, A. Naidoo, B. Dunn, D. Goodall, R. Nanfuka, R. Mufuka-Kapuya, C. Kaleebu, P. Pillay, D. Awio, P. Chirara, M. Dunn, D. Gilks, C. Goodall, R. Kapaata, A. Katuramur, M. Lyagoba, F. Magala, R. Magambo, B. Mataruka, K. McCormick, A. Mugarura, L. Musunga, T. Nabankkema, M. Nkalubo, J. Nkurunziza, P. Parry, C. Robertson, V. Spyer, M. Yirrell, D. Medina Lara, A. Foster, S. Amurwon, J. Nyanzi Wakholi, B. Kigozi, J. Muchabaiwa, L. Muzambi, M. Weller, I. Babiker, A. Bahendeka, S. Bassett, M. Chogo Wapakhabulo, A. Darbyshire, J. Gazzard, B. Gilks, C. Hakim, J. Latif, A. Mapuchere, C. Mugurungi, O. Mugyenyi, P. Burke, C. Jones, S. Newland, C. Rahim, S. Rooney, J. Smith, M. Snowden, W. Steens, J.-M. Breckenridge, A. McLaren, A. Hill, C. Matenga, J. Pozniak, A. Serwadda, D. Peto, T. Palfreeman, A. Borok, M. Clin Infect Dis HIV/AIDS In a randomized comparison of nevirapine or abacavir with zidovudine plus lamivudine, routine viral load monitoring was not performed, yet 27% of individuals with viral failure at week 48 experienced resuppression by week 96 without switching. This supports World Health Organization recommendations that suspected viral failure should trigger adherence counseling and repeat measurement before a treatment switch is considered. Oxford University Press 2014-04-01 2013-12-18 /pmc/articles/PMC3952602/ /pubmed/24352348 http://dx.doi.org/10.1093/cid/cit933 Text en © The Author 2013. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | HIV/AIDS Gupta, Ravindra K. Goodall, Ruth L. Ranopa, Michael Kityo, Cissy Munderi, Paula Lyagoba, Fred Mugarura, Lincoln Gilks, Charles F. Kaleebu, Pontiano Pillay, Deenan Grosskurth, H. Munderi, P. Kabuye, G. Nsibambi, D. Kasirye, R. Zalwango, E. Nakazibwe, M. Kikaire, B. Nassuna, G. Massa, R. Fadhiru, K. Namyalo, M. Zalwango, A. Generous, L. Khauka, P. Rutikarayo, N. Nakahima, W. Mugisha, A. Todd, J. Levin, J. Muyingo, S. Ruberantwari, A. Kaleebu, P. Yirrell, D. Ndembi, N. Lyagoba, F. Hughes, P. Aber, M. Medina Lara, A. Foster, S. Amurwon, J. Mugyenyi, P. Kityo, C. Ssali, F. Tumukunde, D. Otim, T. Kabanda, J. Musana, H. Akao, J. Kyomugisha, H. Byamukama, A. Sabiiti, J. Komugyena, J. Wavamunno, P. Mukiibi, S. Drasiku, A. Byaruhanga, R. Labeja, O. Katundu, P. Tugume, S. Awio, P. Namazzi, A. Bakeinyaga, T. G. Katabira, H. Abaine, D. Tukamushaba, J. Anywar, W. Ojiambo, W. Angweng, E. Murungi, S. Haguma, W. Atwiine, S. Kigozi, J. Latif, A. Hakim, J. Robertson, V. Reid, A. Chidziva, E. Bulaya-Tembo, R. Musoro, G. Taziwa, F. Chimbetete, C. Chakonza, L. Mawora, A. Muvirimi, C. Tinago, G. Svovanapasis, P. Simango, M. Chirema, O. Machingura, J. Mutsai, S. Phiri, M. Bafana, T. Chirara, M. Muchabaiwa, L. Muzambi, M. Katabira, E. Ronald, A. Kambungu, A. Lutwama, F. Nanfuka, A. Walusimbi, J. Nabankema, E. Nalumenya, R. Namuli, T. Kulume, R. Namata, I. Nyachwo, L. Florence, A. Kusiima, A. Lubwama, E. Nairuba, R. Oketta, F. Buluma, E. Waita, R. Ojiambo, H. Sadik, F. Wanyama, J. Nabongo, P. Ochai, R. Muhweezi, D. Gilks, C. Boocock, K. Puddephatt, C. Winogron, D. Bohannon, J. Darbyshire, J. Gibb, M. D. Burke, A. Bray, D. Babiker, A. Walker, S. A. Wilkes, H. Rauchenberger, M. Sheehan, S. Peto, L. Taylor, K. Spyer, M. Ferrier, A. Naidoo, B. Dunn, D. Goodall, R. Nanfuka, R. Mufuka-Kapuya, C. Kaleebu, P. Pillay, D. Awio, P. Chirara, M. Dunn, D. Gilks, C. Goodall, R. Kapaata, A. Katuramur, M. Lyagoba, F. Magala, R. Magambo, B. Mataruka, K. McCormick, A. Mugarura, L. Musunga, T. Nabankkema, M. Nkalubo, J. Nkurunziza, P. Parry, C. Robertson, V. Spyer, M. Yirrell, D. Medina Lara, A. Foster, S. Amurwon, J. Nyanzi Wakholi, B. Kigozi, J. Muchabaiwa, L. Muzambi, M. Weller, I. Babiker, A. Bahendeka, S. Bassett, M. Chogo Wapakhabulo, A. Darbyshire, J. Gazzard, B. Gilks, C. Hakim, J. Latif, A. Mapuchere, C. Mugurungi, O. Mugyenyi, P. Burke, C. Jones, S. Newland, C. Rahim, S. Rooney, J. Smith, M. Snowden, W. Steens, J.-M. Breckenridge, A. McLaren, A. Hill, C. Matenga, J. Pozniak, A. Serwadda, D. Peto, T. Palfreeman, A. Borok, M. High Rate of HIV Resuppression After Viral Failure on First-line Antiretroviral Therapy in the Absence of Switch to Second-line Therapy |
title | High Rate of HIV Resuppression After Viral Failure on First-line Antiretroviral Therapy in the Absence of Switch to Second-line Therapy |
title_full | High Rate of HIV Resuppression After Viral Failure on First-line Antiretroviral Therapy in the Absence of Switch to Second-line Therapy |
title_fullStr | High Rate of HIV Resuppression After Viral Failure on First-line Antiretroviral Therapy in the Absence of Switch to Second-line Therapy |
title_full_unstemmed | High Rate of HIV Resuppression After Viral Failure on First-line Antiretroviral Therapy in the Absence of Switch to Second-line Therapy |
title_short | High Rate of HIV Resuppression After Viral Failure on First-line Antiretroviral Therapy in the Absence of Switch to Second-line Therapy |
title_sort | high rate of hiv resuppression after viral failure on first-line antiretroviral therapy in the absence of switch to second-line therapy |
topic | HIV/AIDS |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952602/ https://www.ncbi.nlm.nih.gov/pubmed/24352348 http://dx.doi.org/10.1093/cid/cit933 |
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highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT labejao highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT katundup highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT tugumes highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT awiop highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT namazzia highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT bakeinyagatg highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT katabirah highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT abained highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT tukamushabaj highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT anywarw highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT ojiambow highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT angwenge highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT murungis highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT hagumaw highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT atwiines highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT kigozij highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT latifa highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT hakimj highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT robertsonv highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT reida highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT chidzivae highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT bulayatembor highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT musorog highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT taziwaf highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT chimbetetec highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT chakonzal highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT maworaa highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT muvirimic highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT tinagog highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT svovanapasisp highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT simangom highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT chiremao highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT machinguraj highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT mutsais highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT phirim highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT bafanat highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT chiraram highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT muchabaiwal highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT muzambim highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT katabirae highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT ronalda highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT kambungua highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT lutwamaf highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nanfukaa highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT walusimbij highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nabankemae highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nalumenyar highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT namulit highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT kulumer highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT namatai highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nyachwol highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT florencea highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT kusiimaa highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT lubwamae highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nairubar highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT okettaf highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT bulumae highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT waitar highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT ojiamboh highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT sadikf highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT wanyamaj highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nabongop highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT ochair highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT muhweezid highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT gilksc highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT boocockk highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT puddephattc highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT winogrond highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT bohannonj highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT darbyshirej highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT gibbmd highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT burkea highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT brayd highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT babikera highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT walkersa highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT wilkesh highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT rauchenbergerm highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT sheehans highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT petol highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT taylork highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT spyerm highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT ferriera highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT naidoob highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT dunnd highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT goodallr highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nanfukar highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT mufukakapuyac highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT kaleebup highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT pillayd highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT awiop highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT chiraram highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT dunnd highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT gilksc highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT goodallr highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT kapaataa highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT katuramurm highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT lyagobaf highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT magalar highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT magambob highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT matarukak highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT mccormicka highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT mugarural highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT musungat highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nabankkemam highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nkaluboj highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nkurunzizap highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT parryc highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT robertsonv highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT spyerm highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT yirrelld highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT medinalaraa highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT fosters highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT amurwonj highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT nyanziwakholib highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT kigozij highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT muchabaiwal highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT muzambim highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT welleri highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT babikera highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT bahendekas highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT bassettm highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT chogowapakhabuloa highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT darbyshirej highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT gazzardb highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT gilksc highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT hakimj highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT latifa highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT mapucherec highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT mugurungio highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT mugyenyip highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT burkec highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT joness highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT newlandc highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT rahims highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT rooneyj highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT smithm highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT snowdenw highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT steensjm highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT breckenridgea highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT mclarena highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT hillc highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT matengaj highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT pozniaka highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT serwaddad highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT petot highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT palfreemana highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy AT borokm highrateofhivresuppressionafterviralfailureonfirstlineantiretroviraltherapyintheabsenceofswitchtosecondlinetherapy |