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Cutaneous Leishmaniasis in North Africa: a review

In North African countries, cutaneous leishmaniasis transmission has been increasing since the 1980s, with a significant increase in the incidence of cases and a spread of the geographical distribution. The disease currently represents a major public health problem with a productivity gap and an imp...

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Autores principales: Aoun, Karim, Bouratbine, Aïda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952656/
https://www.ncbi.nlm.nih.gov/pubmed/24626301
http://dx.doi.org/10.1051/parasite/2014014
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author Aoun, Karim
Bouratbine, Aïda
author_facet Aoun, Karim
Bouratbine, Aïda
author_sort Aoun, Karim
collection PubMed
description In North African countries, cutaneous leishmaniasis transmission has been increasing since the 1980s, with a significant increase in the incidence of cases and a spread of the geographical distribution. The disease currently represents a major public health problem with a productivity gap and an impediment for development, which results in dramatic socioeconomic and psycho-sanitary impacts. The incidence is more than thousands of cases every year in Algeria, Libya, Morocco, and Tunisia. In Egypt, only a few dozen cases per year are reported, mainly in the Sinai Peninsula. Three Leishmania species, associated with distinct eco-epidemiological and clinical patterns, are involved, namely Leishmania infantum, L. major, and L. tropica. However, L. major is by far the most frequent in Algeria, Libya, and Tunisia, with more than 90% of the registered cases. It is mainly encountered in rural areas under semi-arid, arid and Saharan climates. Leishmania tropica is more prevalent in Morocco, reaching 30–40% of isolates in some districts. Much data is still missing concerning the risk factors of the infection and the lesion development, as well as vector and reservoir ecology and behavior. The knowledge of such parameters, following multidisciplinary and integrated approaches, is crucial for better management and control of the disease, that also faces a lack of resources and efficient control measures.
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spelling pubmed-39526562014-03-27 Cutaneous Leishmaniasis in North Africa: a review Aoun, Karim Bouratbine, Aïda Parasite Research Article In North African countries, cutaneous leishmaniasis transmission has been increasing since the 1980s, with a significant increase in the incidence of cases and a spread of the geographical distribution. The disease currently represents a major public health problem with a productivity gap and an impediment for development, which results in dramatic socioeconomic and psycho-sanitary impacts. The incidence is more than thousands of cases every year in Algeria, Libya, Morocco, and Tunisia. In Egypt, only a few dozen cases per year are reported, mainly in the Sinai Peninsula. Three Leishmania species, associated with distinct eco-epidemiological and clinical patterns, are involved, namely Leishmania infantum, L. major, and L. tropica. However, L. major is by far the most frequent in Algeria, Libya, and Tunisia, with more than 90% of the registered cases. It is mainly encountered in rural areas under semi-arid, arid and Saharan climates. Leishmania tropica is more prevalent in Morocco, reaching 30–40% of isolates in some districts. Much data is still missing concerning the risk factors of the infection and the lesion development, as well as vector and reservoir ecology and behavior. The knowledge of such parameters, following multidisciplinary and integrated approaches, is crucial for better management and control of the disease, that also faces a lack of resources and efficient control measures. EDP Sciences 2014 2014-03-14 /pmc/articles/PMC3952656/ /pubmed/24626301 http://dx.doi.org/10.1051/parasite/2014014 Text en © K. Aoun & A. Bouratbine, published by EDP Sciences, 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Aoun, Karim
Bouratbine, Aïda
Cutaneous Leishmaniasis in North Africa: a review
title Cutaneous Leishmaniasis in North Africa: a review
title_full Cutaneous Leishmaniasis in North Africa: a review
title_fullStr Cutaneous Leishmaniasis in North Africa: a review
title_full_unstemmed Cutaneous Leishmaniasis in North Africa: a review
title_short Cutaneous Leishmaniasis in North Africa: a review
title_sort cutaneous leishmaniasis in north africa: a review
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952656/
https://www.ncbi.nlm.nih.gov/pubmed/24626301
http://dx.doi.org/10.1051/parasite/2014014
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