Changes in Malaria Parasite Drug Resistance in an Endemic Population Over a 25-Year Period With Resulting Genomic Evidence of Selection

Background. Analysis of genome-wide polymorphism in many organisms has potential to identify genes under recent selection. However, data on historical allele frequency changes are rarely available for direct confirmation. Methods. We genotyped single nucleotide polymorphisms (SNPs) in 4 Plasmodium f...

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Detalles Bibliográficos
Autores principales: Nwakanma, Davis C., Duffy, Craig W., Amambua-Ngwa, Alfred, Oriero, Eniyou C., Bojang, Kalifa A., Pinder, Margaret, Drakeley, Chris J., Sutherland, Colin J., Milligan, Paul J., MacInnis, Bronwyn, Kwiatkowski, Dominic P., Clark, Taane G., Greenwood, Brian M., Conway, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952670/
https://www.ncbi.nlm.nih.gov/pubmed/24265439
http://dx.doi.org/10.1093/infdis/jit618

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