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Unbiased, scalable sampling of protein loop conformations from probabilistic priors
BACKGROUND: Protein loops are flexible structures that are intimately tied to function, but understanding loop motion and generating loop conformation ensembles remain significant computational challenges. Discrete search techniques scale poorly to large loops, optimization and molecular dynamics te...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953323/ https://www.ncbi.nlm.nih.gov/pubmed/24565175 http://dx.doi.org/10.1186/1472-6807-13-S1-S9 |