Caspase-1-Dependent and -Independent Cell Death Pathways in Burkholderia pseudomallei Infection of Macrophages

The cytosolic pathogen Burkholderia pseudomallei and causative agent of melioidosis has been shown to regulate IL-1β and IL-18 production through NOD-like receptor NLRP3 and pyroptosis via NLRC4. Downstream signalling pathways of those receptors and other cell death mechanisms induced during B. pseu...

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Detalles Bibliográficos
Autores principales: Bast, Antje, Krause, Kathrin, Schmidt, Imke H. E., Pudla, Matsayapan, Brakopp, Stefanie, Hopf, Verena, Breitbach, Katrin, Steinmetz, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953413/
https://www.ncbi.nlm.nih.gov/pubmed/24626296
http://dx.doi.org/10.1371/journal.ppat.1003986

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