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Immune Suppression by Neutrophils in HIV-1 Infection: Role of PD-L1/PD-1 Pathway

HIV-1 infection is associated with a progressive loss of T cell functional capacity and reduced responsiveness to antigenic stimuli. The mechanisms underlying T cell dysfunction in HIV-1/AIDS are not completely understood. Multiple studies have shown that binding of program death ligand 1 (PD-L1) on...

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Detalles Bibliográficos
Autores principales:	Bowers, Nathan L., Helton, E. Scott, Huijbregts, Richard P. H., Goepfert, Paul A., Heath, Sonya L., Hel, Zdenek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953441/ https://www.ncbi.nlm.nih.gov/pubmed/24626392 http://dx.doi.org/10.1371/journal.ppat.1003993

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