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Atheroprotective Pulsatile Flow Induces Ubiquitin-Proteasome–Mediated Degradation of Programmed Cell Death 4 in Endothelial Cells

OBJECTIVES: We recently found low level of tumor suppressor programmed cell death 4 (PDCD4) associated with reduced atherosclerotic plaque area (unpublished). We investigated whether atheroprotective unidirectional pulsatile shear stress affects the expression of PDCD4 in endothelial cells. METHODS...

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Detalles Bibliográficos
Autores principales: Ge, Cheng, Song, Jiantao, Chen, Liang, Wang, Lin, Chen, Yifei, Liu, Xinxin, Zhang, Yu, Zhang, Lining, Zhang, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953479/
https://www.ncbi.nlm.nih.gov/pubmed/24626527
http://dx.doi.org/10.1371/journal.pone.0091564