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Oleanolic Acid Suppresses Aerobic Glycolysis in Cancer Cells by Switching Pyruvate Kinase Type M Isoforms

Warburg effect, one of the hallmarks for cancer cells, is characterized by metabolic switch from mitochondrial oxidative phosphorylation to aerobic glycolysis. In recent years, increased expression level of pyruvate kinase M2 (PKM2) has been found to be the culprit of enhanced aerobic glycolysis in...

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Detalles Bibliográficos
Autores principales:	Liu, Jia, Wu, Ning, Ma, Leina, Liu, Ming, Liu, Ge, Zhang, Yuyan, Lin, Xiukun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953484/ https://www.ncbi.nlm.nih.gov/pubmed/24626155 http://dx.doi.org/10.1371/journal.pone.0091606

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