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Fixation-induced cell blebbing on spread cells inversely correlates with phosphatidylinositol 4,5-bisphosphate level in the plasma membrane

While most attention has been focused on physiologically generated blebs, the molecular mechanisms for fixation-induced cell blebbing are less investigated. We show that protein-fixing (e.g. aldehydes and picric acid) but not lipid-stabilizing (e.g. OsO(4) and KMnO(4)) fixatives induce blebbing on s...

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Detalles Bibliográficos
Autores principales: Zhao, Siyuan, Liao, Huanhuan, Ao, Meiying, Wu, Li, Zhang, Xiaojun, Chen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953720/
https://www.ncbi.nlm.nih.gov/pubmed/24649401
http://dx.doi.org/10.1016/j.fob.2014.02.003

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