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Genotyping of ancient Mycobacterium tuberculosis strains reveals historic genetic diversity
The evolutionary history of the Mycobacterium tuberculosis complex (MTBC) has previously been studied by analysis of sequence diversity in extant strains, but not addressed by direct examination of strain genotypes in archaeological remains. Here, we use ancient DNA sequencing to type 11 single nucl...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953847/ https://www.ncbi.nlm.nih.gov/pubmed/24573854 http://dx.doi.org/10.1098/rspb.2013.3236 |