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Hydrogen peroxide signaling in vascular endothelial cells

Redox signaling is implicated in different physiological and pathological events in the vasculature. Among the different reactive oxygen species, hydrogen peroxide (H(2)O(2)) is a very good candidate to perform functions as an intracellular messenger in the regulation of several biological events. I...

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Detalles Bibliográficos
Autores principales: Bretón-Romero, Rosa, Lamas, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953958/
https://www.ncbi.nlm.nih.gov/pubmed/24634835
http://dx.doi.org/10.1016/j.redox.2014.02.005
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author Bretón-Romero, Rosa
Lamas, Santiago
author_facet Bretón-Romero, Rosa
Lamas, Santiago
author_sort Bretón-Romero, Rosa
collection PubMed
description Redox signaling is implicated in different physiological and pathological events in the vasculature. Among the different reactive oxygen species, hydrogen peroxide (H(2)O(2)) is a very good candidate to perform functions as an intracellular messenger in the regulation of several biological events. In this review, we summarize the main physiological sources of H(2)O(2) in the endothelium and the molecular mechanisms by which it is able to act as a signaling mediator in the vasculature.
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spelling pubmed-39539582014-03-14 Hydrogen peroxide signaling in vascular endothelial cells Bretón-Romero, Rosa Lamas, Santiago Redox Biol Review Article Redox signaling is implicated in different physiological and pathological events in the vasculature. Among the different reactive oxygen species, hydrogen peroxide (H(2)O(2)) is a very good candidate to perform functions as an intracellular messenger in the regulation of several biological events. In this review, we summarize the main physiological sources of H(2)O(2) in the endothelium and the molecular mechanisms by which it is able to act as a signaling mediator in the vasculature. Elsevier 2014-03-01 /pmc/articles/PMC3953958/ /pubmed/24634835 http://dx.doi.org/10.1016/j.redox.2014.02.005 Text en © 2014 The Authors https://creativecommons.org/licenses/by-nc-nd/3.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License (https://creativecommons.org/licenses/by-nc-nd/3.0/) .
spellingShingle Review Article
Bretón-Romero, Rosa
Lamas, Santiago
Hydrogen peroxide signaling in vascular endothelial cells
title Hydrogen peroxide signaling in vascular endothelial cells
title_full Hydrogen peroxide signaling in vascular endothelial cells
title_fullStr Hydrogen peroxide signaling in vascular endothelial cells
title_full_unstemmed Hydrogen peroxide signaling in vascular endothelial cells
title_short Hydrogen peroxide signaling in vascular endothelial cells
title_sort hydrogen peroxide signaling in vascular endothelial cells
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953958/
https://www.ncbi.nlm.nih.gov/pubmed/24634835
http://dx.doi.org/10.1016/j.redox.2014.02.005
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