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Hydrogen peroxide signaling in vascular endothelial cells
Redox signaling is implicated in different physiological and pathological events in the vasculature. Among the different reactive oxygen species, hydrogen peroxide (H(2)O(2)) is a very good candidate to perform functions as an intracellular messenger in the regulation of several biological events. I...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953958/ https://www.ncbi.nlm.nih.gov/pubmed/24634835 http://dx.doi.org/10.1016/j.redox.2014.02.005 |
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author | Bretón-Romero, Rosa Lamas, Santiago |
author_facet | Bretón-Romero, Rosa Lamas, Santiago |
author_sort | Bretón-Romero, Rosa |
collection | PubMed |
description | Redox signaling is implicated in different physiological and pathological events in the vasculature. Among the different reactive oxygen species, hydrogen peroxide (H(2)O(2)) is a very good candidate to perform functions as an intracellular messenger in the regulation of several biological events. In this review, we summarize the main physiological sources of H(2)O(2) in the endothelium and the molecular mechanisms by which it is able to act as a signaling mediator in the vasculature. |
format | Online Article Text |
id | pubmed-3953958 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-39539582014-03-14 Hydrogen peroxide signaling in vascular endothelial cells Bretón-Romero, Rosa Lamas, Santiago Redox Biol Review Article Redox signaling is implicated in different physiological and pathological events in the vasculature. Among the different reactive oxygen species, hydrogen peroxide (H(2)O(2)) is a very good candidate to perform functions as an intracellular messenger in the regulation of several biological events. In this review, we summarize the main physiological sources of H(2)O(2) in the endothelium and the molecular mechanisms by which it is able to act as a signaling mediator in the vasculature. Elsevier 2014-03-01 /pmc/articles/PMC3953958/ /pubmed/24634835 http://dx.doi.org/10.1016/j.redox.2014.02.005 Text en © 2014 The Authors https://creativecommons.org/licenses/by-nc-nd/3.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License (https://creativecommons.org/licenses/by-nc-nd/3.0/) . |
spellingShingle | Review Article Bretón-Romero, Rosa Lamas, Santiago Hydrogen peroxide signaling in vascular endothelial cells |
title | Hydrogen peroxide signaling in vascular endothelial cells |
title_full | Hydrogen peroxide signaling in vascular endothelial cells |
title_fullStr | Hydrogen peroxide signaling in vascular endothelial cells |
title_full_unstemmed | Hydrogen peroxide signaling in vascular endothelial cells |
title_short | Hydrogen peroxide signaling in vascular endothelial cells |
title_sort | hydrogen peroxide signaling in vascular endothelial cells |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953958/ https://www.ncbi.nlm.nih.gov/pubmed/24634835 http://dx.doi.org/10.1016/j.redox.2014.02.005 |
work_keys_str_mv | AT bretonromerorosa hydrogenperoxidesignalinginvascularendothelialcells AT lamassantiago hydrogenperoxidesignalinginvascularendothelialcells |