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Improved Cross Validation of a Static Ubiquitin Structure Derived from High Precision Residual Dipolar Couplings Measured in a Drug-Based Liquid Crystalline Phase

[Image: see text] The antibiotic squalamine forms a lyotropic liquid crystal at very low concentrations in water (0.3-3.5% w/v), which remains stable over a wide range of temperature (1-40 °C) and pH (4-8). Squalamine is positively charged, and comparison of the alignment of ubiquitin relative to 36...

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Detalles Bibliográficos
Autores principales: Maltsev, Alexander S., Grishaev, Alexander, Roche, Julien, Zasloff, Michael, Bax, Ad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954408/
https://www.ncbi.nlm.nih.gov/pubmed/24568736
http://dx.doi.org/10.1021/ja4132642