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Caeruleanone A, a Rotenoid with a New Arrangement of the D-Ring from the Fruits of Millettia caerulea
[Image: see text] Caeruleanone A (1), a novel rotenoid with an unprecedented arrangement of the D-ring, was isolated with another two new analogues, caeruleanones B (2) and C (3), together with 11 known rotenoids from the fruits of Millettia caerulea. The structures of the new compounds were determi...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954433/ https://www.ncbi.nlm.nih.gov/pubmed/24552419 http://dx.doi.org/10.1021/ol500266z |
| _version_ | 1782307476495925248 |
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| author | Bueno Pérez, Lynette Pan, Li Muñoz Acuña, Ulyana Li, Jie Chai, Hee-Byung Gallucci, Judith C. Ninh, Tran Ngoc Carcache de Blanco, Esperanza J. Soejarto, Djaja D. Kinghorn, A. Douglas |
| author_facet | Bueno Pérez, Lynette Pan, Li Muñoz Acuña, Ulyana Li, Jie Chai, Hee-Byung Gallucci, Judith C. Ninh, Tran Ngoc Carcache de Blanco, Esperanza J. Soejarto, Djaja D. Kinghorn, A. Douglas |
| author_sort | Bueno Pérez, Lynette |
| collection | PubMed |
| description | [Image: see text] Caeruleanone A (1), a novel rotenoid with an unprecedented arrangement of the D-ring, was isolated with another two new analogues, caeruleanones B (2) and C (3), together with 11 known rotenoids from the fruits of Millettia caerulea. The structures of the new compounds were determined by spectroscopic data analysis, with that of 1 being confirmed by single-crystal X-ray diffraction. Compounds 2 and 3 displayed potent mitochondrial transmembrane potential inhibitory and quinone reductase induction activities. |
| format | Online Article Text |
| id | pubmed-3954433 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | American Chemical
Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-39544332015-02-19 Caeruleanone A, a Rotenoid with a New Arrangement of the D-Ring from the Fruits of Millettia caerulea Bueno Pérez, Lynette Pan, Li Muñoz Acuña, Ulyana Li, Jie Chai, Hee-Byung Gallucci, Judith C. Ninh, Tran Ngoc Carcache de Blanco, Esperanza J. Soejarto, Djaja D. Kinghorn, A. Douglas Org Lett [Image: see text] Caeruleanone A (1), a novel rotenoid with an unprecedented arrangement of the D-ring, was isolated with another two new analogues, caeruleanones B (2) and C (3), together with 11 known rotenoids from the fruits of Millettia caerulea. The structures of the new compounds were determined by spectroscopic data analysis, with that of 1 being confirmed by single-crystal X-ray diffraction. Compounds 2 and 3 displayed potent mitochondrial transmembrane potential inhibitory and quinone reductase induction activities. American Chemical Society 2014-02-19 2014-03-07 /pmc/articles/PMC3954433/ /pubmed/24552419 http://dx.doi.org/10.1021/ol500266z Text en Copyright © 2014 American Chemical Society |
| spellingShingle | Bueno Pérez, Lynette Pan, Li Muñoz Acuña, Ulyana Li, Jie Chai, Hee-Byung Gallucci, Judith C. Ninh, Tran Ngoc Carcache de Blanco, Esperanza J. Soejarto, Djaja D. Kinghorn, A. Douglas Caeruleanone A, a Rotenoid with a New Arrangement of the D-Ring from the Fruits of Millettia caerulea |
| title | Caeruleanone A, a Rotenoid with a New Arrangement
of the D-Ring from the Fruits of Millettia caerulea |
| title_full | Caeruleanone A, a Rotenoid with a New Arrangement
of the D-Ring from the Fruits of Millettia caerulea |
| title_fullStr | Caeruleanone A, a Rotenoid with a New Arrangement
of the D-Ring from the Fruits of Millettia caerulea |
| title_full_unstemmed | Caeruleanone A, a Rotenoid with a New Arrangement
of the D-Ring from the Fruits of Millettia caerulea |
| title_short | Caeruleanone A, a Rotenoid with a New Arrangement
of the D-Ring from the Fruits of Millettia caerulea |
| title_sort | caeruleanone a, a rotenoid with a new arrangement
of the d-ring from the fruits of millettia caerulea |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954433/ https://www.ncbi.nlm.nih.gov/pubmed/24552419 http://dx.doi.org/10.1021/ol500266z |
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