Cargando…

Elucidation of Structural Elements for Selectivity across Monoamine Transporters: Novel 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues

[Image: see text] 2-[(Diphenylmethyl)sulfinyl]acetamide (modafinil, (±)-1) is a unique dopamine uptake inhibitor that binds the dopamine transporter (DAT) differently than cocaine and may have potential for the treatment of psychostimulant abuse. To further investigate structural requirements for th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Okunola-Bakare, Oluyomi M., Cao, Jianjing, Kopajtic, Theresa, Katz, Jonathan L., Loland, Claus J., Shi, Lei, Newman, Amy Hauck
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954497/ https://www.ncbi.nlm.nih.gov/pubmed/24494745 http://dx.doi.org/10.1021/jm401754x

Ejemplares similares

Diphenylmethyl benzoate
por: Kaur, Manpreet, et al.
Publicado: (2012)

Diphenylmethyl isothiocyanate
por: Zhao, Pei-Hua, et al.
Publicado: (2012)

A Straightforward Diphenylmethyl Protection Method and Deprotection of Some Pyrimidine Nucleosides
por: Saudi, Milind, et al.
Publicado: (2013)

Cognitive profiling and proteomic analysis of the modafinil analogue S-CE-123 in experienced aged rats
por: Gyertyán, István, et al.
Publicado: (2021)

Synthetic exploration of sulfinyl radicals using sulfinyl sulfones
por: Wang, Zikun, et al.
Publicado: (2021)

1-Diphenylmethyl-4-ethylpiperazine-1,4-diium dichloride
por: Qiao, Hong-Yun, et al.
Publicado: (2010)

Modafinil in the treatment of excessive sleepiness
por: Schwartz, Jonathan RL
Publicado: (2009)

Fixed drug eruptions with modafinil
por: Ghoshal, Loknath, et al.
Publicado: (2015)

N,N′-Bis(diphenylmethyl)benzene-1,4-diamine
por: Al-Fahdawi, Aeed S., et al.
Publicado: (2013)

(3S,5R,6S)-Diphenylmethyl 1-oxo-6-bromopenicillanate
por: Soundararajan, Krishnan, et al.
Publicado: (2020)

Modafinil does not reduce cocaine use in methadone-maintained individuals
por: DeVito, Elise E., et al.
Publicado: (2022)

(Z)-1-Diphenylmethyl-4-(3-phenylprop-2-enyl)piperazine
por: Shivaprakash, S., et al.
Publicado: (2014)

Modafinil in the media: Metaphors, medicalisation and the body
por: Coveney, Catherine M., et al.
Publicado: (2009)

Modafinil modulation of the default mode network
por: Minzenberg, Michael J., et al.
Publicado: (2010)

Modafinil-induced Fixed Drug Eruption
por: Gaikwad, Girish Vasant, et al.
Publicado: (2012)

A rare case modafinil dependence
por: Krishnan, Raman, et al.
Publicado: (2015)

meso-1-{[2-(Propyl-1-sulfinyl)ethyl]sulfinyl}propane
por: Wardell, Solange M. S. V., et al.
Publicado: (2010)

Modafinil Induces Rapid-Onset Behavioral Sensitization and Cross-Sensitization with Cocaine in Mice: Implications for the Addictive Potential of Modafinil
por: Wuo-Silva, Raphael, et al.
Publicado: (2016)

The Novel Analogue of Modafinil CE-158 Protects Social Memory against Interference and Triggers the Release of Dopamine in the Nucleus Accumbens of Mice
por: Ebner, Karl, et al.
Publicado: (2022)

Diphenylmethyl selenocyanate attenuates malachite green induced oxidative injury through antioxidation & inhibition of DNA damage in mice
por: Das, Jayanta Kumar, et al.
Publicado: (2013)

Controlled (Co)Polymerization of Methacrylates Using a Novel Symmetrical Trithiocarbonate RAFT Agent Bearing Diphenylmethyl Groups
por: Robles Grana, Alvaro Leonel, et al.
Publicado: (2021)

The mechanism and pharmacodynamics of 2-((1H-indol-3-yl)thio/sulfinyl)-N-pheny acetamide derivative as a novel inhibitor against human respiratory syncytial virus
por: Cheng, Ningning, et al.
Publicado: (2022)

Mechanisms of modafinil: A review of current research
por: Gerrard, Paul, et al.
Publicado: (2007)

A Retrospective Review of Supratherapeutic Modafinil Exposures
por: Carstairs, Shaun D., et al.
Publicado: (2010)

Synthesis and psychobiological evaluation of modafinil analogs in mice
por: Lari, Arezou, et al.
Publicado: (2013)

Modafinil decreases anxiety-like behaviour in zebrafish
por: Johnson, Adrian, et al.
Publicado: (2017)

Psychostimulant Use Disorder, an Unmet Therapeutic Goal: Can Modafinil Narrow the Gap?
por: Hersey, Melinda, et al.
Publicado: (2021)

Enantioselective Synthesis of (+)-Coerulescine by a Phase-Transfer Catalytic Allylation of Diphenylmethyl tert-Butyl α-(2-Nitrophenyl)Malonate
por: Lee, Sangki, et al.
Publicado: (2020)

Kleine-Levine syndrome in an adolescent female and response to modafinil
por: Aggarwal, Ashish, et al.
Publicado: (2011)

Waking up to modafinil in shift work sleep disorder
por: Gude, Dilip
Publicado: (2011)

The successful treatment of hypercapnic respiratory failure with oral modafinil
por: Parnell, Helen, et al.
Publicado: (2014)

Cortico-Amygdala-Striatal Activation by Modafinil/Flecainide Combination
por: Vodovar, Dominique, et al.
Publicado: (2018)

Simple Synthesis of Modafinil Derivatives and Their Anti-inflammatory Activity
por: Jung, Jae-Chul, et al.
Publicado: (2012)

Postoperative Cognitive Dysfunction in the Elderly: A Role for Modafinil
por: Desai, Ronak, et al.
Publicado: (2022)

Modern Stereoselective Synthesis of Chiral Sulfinyl Compounds
por: Wojaczyńska, Elżbieta, et al.
Publicado: (2020)

Atrial Septal Aneurysm Mimicking a Cor Triatriatum Sinister: A Case Report and Review of the Literature
por: Oyedeji, Adebayo Tolulope, et al.
Publicado: (2012)

2-[(Cyclopenta-1,3-dien-2-yl)diphenylmethyl]-1-methyl-1H-imidazole
por: Sun, Qi, et al.
Publicado: (2010)

A novel study of screening and confirmation of modafinil, adrafinil and their metabolite modafinilic acid under EI-GC-MS and ESI-LC-MS-MS ionization
por: Dubey, S., et al.
Publicado: (2009)

1-Diphenylmethyl-4-[3-(4-fluorobenzoyl)propyl]piperazine-1,4-diium dichloride monohydrate
por: Wang, Jing, et al.
Publicado: (2011)

Modafinil normalized hyperreflexia after spinal transection in adult rats
por: Yates, Charlotte C., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_berj46jmq4n618d8mpqbfrp26v