Quantitation of Glucocorticoid Receptor DNA-Binding Dynamics by Single-Molecule Microscopy and FRAP

Recent advances in live cell imaging have provided a wealth of data on the dynamics of transcription factors. However, a consistent quantitative description of these dynamics, explaining how transcription factors find their target sequences in the vast amount of DNA inside the nucleus, is still lack...

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Detalles Bibliográficos
Autores principales: Groeneweg, Femke L., van Royen, Martin E., Fenz, Susanne, Keizer, Veer I. P., Geverts, Bart, Prins, Jurrien, de Kloet, E. Ron, Houtsmuller, Adriaan B., Schmidt, Thomas S., Schaaf, Marcel J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954550/
https://www.ncbi.nlm.nih.gov/pubmed/24632838
http://dx.doi.org/10.1371/journal.pone.0090532

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