An Fc Domain Protein–Small Molecule Conjugate as an Enhanced Immunomodulator

[Image: see text] Proteins as well as small molecules have demonstrated success as therapeutic agents, but their pharmacologic properties sometimes fall short against particular drug targets. Although the adenosine 2a receptor (A(2A)R) has been identified as a promising target for immunotherapy, sma...

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Detalles Bibliográficos
Autores principales: Chiang, Meng-Jung, Holbert, Marc A., Kalin, Jay H., Ahn, Young-Hoon, Giddens, John, Amin, Mohammed N., Taylor, Martin S., Collins, Samuel L., Chan-Li, Yee, Waickman, Adam, Hsiao, Po-Yuan, Bolduc, David, Leahy, Daniel J., Horton, Maureen R., Wang, Lai-Xi, Powell, Jonathan D., Cole, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954559/
https://www.ncbi.nlm.nih.gov/pubmed/24533830
http://dx.doi.org/10.1021/ja5006674

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