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Study of Hydatidosis-Attributed Mortality in Endemic Area

BACKGROUND: Cystic hydatid disease is still an important health problem in European Mediterranean areas. In spite of being traditionally considered as a “benign” pathology, cystic echinococcosis is an important cause of morbidity in these areas. Nevertheless, there are few analyses of mortality attr...

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Autores principales: Belhassen-García, Moncef, Romero-Alegria, Angela, Velasco-Tirado, Virginia, Alonso-Sardón, Montserrat, Lopez-Bernus, Amparo, Alvela-Suarez, Lucia, del Villar, Luis Perez, Carpio-Perez, Adela, Galindo-Perez, Inmaculada, Cordero-Sanchez, Miguel, Pardo-Lledias, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954695/
https://www.ncbi.nlm.nih.gov/pubmed/24632824
http://dx.doi.org/10.1371/journal.pone.0091342
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author Belhassen-García, Moncef
Romero-Alegria, Angela
Velasco-Tirado, Virginia
Alonso-Sardón, Montserrat
Lopez-Bernus, Amparo
Alvela-Suarez, Lucia
del Villar, Luis Perez
Carpio-Perez, Adela
Galindo-Perez, Inmaculada
Cordero-Sanchez, Miguel
Pardo-Lledias, Javier
author_facet Belhassen-García, Moncef
Romero-Alegria, Angela
Velasco-Tirado, Virginia
Alonso-Sardón, Montserrat
Lopez-Bernus, Amparo
Alvela-Suarez, Lucia
del Villar, Luis Perez
Carpio-Perez, Adela
Galindo-Perez, Inmaculada
Cordero-Sanchez, Miguel
Pardo-Lledias, Javier
author_sort Belhassen-García, Moncef
collection PubMed
description BACKGROUND: Cystic hydatid disease is still an important health problem in European Mediterranean areas. In spite of being traditionally considered as a “benign” pathology, cystic echinococcosis is an important cause of morbidity in these areas. Nevertheless, there are few analyses of mortality attributed to human hydatidosis. OBJECTIVE: To describe the epidemiology, the mortality rate and the causes of mortality due to E. granulosus infection in an endemic area. METHODOLOGY: A retrospective study followed up over a period of 14 years (1998–2011). PRINCIPAL FINDINGS: Of the 567 patients diagnosed with hydatid disease over the period 1998–2011, eleven deaths directly related to hydatid disease complications were recorded. Ten patients (90.9%) died due to infectious complications and the remaining one (9.1%) died due to mechanical complications after a massive hemoptysis. We registered a case fatality rate of 1.94% and a mortality rate of 3.1 per 100.000 inhabitants. CONCLUSIONS: Hydatidosis is still a frequent parasitic disease that causes a considerable mortality. The main causes of mortality in patients with hydatidosis are complications related to the rupture of CE cysts with supurative collangitis. Therefore, an expectant management can be dangerous and it must be only employed in well-selected patients.
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spelling pubmed-39546952014-03-18 Study of Hydatidosis-Attributed Mortality in Endemic Area Belhassen-García, Moncef Romero-Alegria, Angela Velasco-Tirado, Virginia Alonso-Sardón, Montserrat Lopez-Bernus, Amparo Alvela-Suarez, Lucia del Villar, Luis Perez Carpio-Perez, Adela Galindo-Perez, Inmaculada Cordero-Sanchez, Miguel Pardo-Lledias, Javier PLoS One Research Article BACKGROUND: Cystic hydatid disease is still an important health problem in European Mediterranean areas. In spite of being traditionally considered as a “benign” pathology, cystic echinococcosis is an important cause of morbidity in these areas. Nevertheless, there are few analyses of mortality attributed to human hydatidosis. OBJECTIVE: To describe the epidemiology, the mortality rate and the causes of mortality due to E. granulosus infection in an endemic area. METHODOLOGY: A retrospective study followed up over a period of 14 years (1998–2011). PRINCIPAL FINDINGS: Of the 567 patients diagnosed with hydatid disease over the period 1998–2011, eleven deaths directly related to hydatid disease complications were recorded. Ten patients (90.9%) died due to infectious complications and the remaining one (9.1%) died due to mechanical complications after a massive hemoptysis. We registered a case fatality rate of 1.94% and a mortality rate of 3.1 per 100.000 inhabitants. CONCLUSIONS: Hydatidosis is still a frequent parasitic disease that causes a considerable mortality. The main causes of mortality in patients with hydatidosis are complications related to the rupture of CE cysts with supurative collangitis. Therefore, an expectant management can be dangerous and it must be only employed in well-selected patients. Public Library of Science 2014-03-14 /pmc/articles/PMC3954695/ /pubmed/24632824 http://dx.doi.org/10.1371/journal.pone.0091342 Text en © 2014 Belhassen-García et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Belhassen-García, Moncef
Romero-Alegria, Angela
Velasco-Tirado, Virginia
Alonso-Sardón, Montserrat
Lopez-Bernus, Amparo
Alvela-Suarez, Lucia
del Villar, Luis Perez
Carpio-Perez, Adela
Galindo-Perez, Inmaculada
Cordero-Sanchez, Miguel
Pardo-Lledias, Javier
Study of Hydatidosis-Attributed Mortality in Endemic Area
title Study of Hydatidosis-Attributed Mortality in Endemic Area
title_full Study of Hydatidosis-Attributed Mortality in Endemic Area
title_fullStr Study of Hydatidosis-Attributed Mortality in Endemic Area
title_full_unstemmed Study of Hydatidosis-Attributed Mortality in Endemic Area
title_short Study of Hydatidosis-Attributed Mortality in Endemic Area
title_sort study of hydatidosis-attributed mortality in endemic area
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954695/
https://www.ncbi.nlm.nih.gov/pubmed/24632824
http://dx.doi.org/10.1371/journal.pone.0091342
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