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An A91V SNP in the Perforin Gene Is Frequently Found in NK/T-Cell Lymphomas

NK/T-cell lymphoma (NKTCL) is the most frequent EBV-related NK/T-cell disease. Its clinical manifestations overlap with those of familial haemophagocytic lymphohistiocytosis (FHLH). Since PERFORIN (PRF1) mutations are present in FHLH, we analysed its role in a series of 12 nasal and 12 extranasal-NK...

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Detalles Bibliográficos
Autores principales:	Manso, Rebeca, Rodríguez-Pinilla, Socorro María, Lombardia, Luis, Ruiz de Garibay, Gorka, del Mar López, Maria, Requena, Luis, Sánchez, Lydia, Sánchez-Beato, Margarita, Piris, Miguel Ángel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954696/ https://www.ncbi.nlm.nih.gov/pubmed/24632576 http://dx.doi.org/10.1371/journal.pone.0091521

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