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SHP-2 Binds to Caveolin-1 and Regulates Src Activity via Competitive Inhibition of CSK in Response to H(2)O(2) in Astrocytes

Reactive oxygen species (ROS) regulate diverse cellular functions by triggering signal transduction events, such as Src and mitogen-activated protein (MAP) kinases. Here, we report the role of caveolin-1 and Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP-2) in H(2)O(2)-induced...

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Detalles Bibliográficos
Autores principales:	Jo, Ara, Park, Hyunju, Lee, Sung-Hee, Ahn, So-Hee, Kim, Hee Ja, Park, Eun-Mi, Choi, Youn-Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954793/ https://www.ncbi.nlm.nih.gov/pubmed/24632723 http://dx.doi.org/10.1371/journal.pone.0091582

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