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SOCS3 Promoter Hypermethylation Is a Favorable Prognosticator and a Novel Indicator for G-CIMP-Positive GBM Patients

BACKGROUND: Hypermethylation of the suppressor of cytokine signaling 3(SOCS3) promoter has been reported to predict a poor prognosis in several cancers including glioblstoma multiforme (GBM). We explored the function of SOCS3 promoter hypermethylation in GBM cohorts, including analysis of the CpG is...

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Detalles Bibliográficos
Autores principales:	Feng, Ying, Wang, Zheng, Bao, Zhaoshi, Yan, Wei, You, Gan, Wang, Yinyan, Hu, Huimin, Zhang, Wei, Zhang, Quangeng, Jiang, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954800/ https://www.ncbi.nlm.nih.gov/pubmed/24633048 http://dx.doi.org/10.1371/journal.pone.0091829

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