Overexpression of Down Syndrome Cell Adhesion Molecule impairs precise synaptic targeting

Fragile X syndrome is caused by loss of Fragile X Mental Retardation Protein (FMRP), an RNA binding protein that suppresses protein translation. Here, we identified Down Syndrome Cell Adhesion Molecule (Dscam) RNA, a molecule involved in neural development and implicated in Down syndrome, bound to F...

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Detalles Bibliográficos
Autores principales: Cvetkovska, Vedrana, Hibbert, Alexa D., Emran, Farida, Chen, Brian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954815/
https://www.ncbi.nlm.nih.gov/pubmed/23666178
http://dx.doi.org/10.1038/nn.3396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954815/
https://www.ncbi.nlm.nih.gov/pubmed/23666178
http://dx.doi.org/10.1038/nn.3396

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