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The Insulin Resistance Grb14 Adaptor Protein Promotes Thyroid Cancer Ret Signaling and Progression

The growth factor receptor-bound protein (Grb) 14 is an adapter molecule of the Grb7/10/14 family with characteristic BPS domains serving to avidly bind tyrosine kinases. Grb14 inhibits insulin receptor (IR) catalytic activity through interaction with the BPS domain and impedes peptide substrate bin...

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Detalles Bibliográficos
Autores principales:	Balogh, Katalin, Asa, Sylvia L., Zheng, Lei, Cassol, Clarissa, Cheng, Sonia, Ezzat, Shereen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954818/ https://www.ncbi.nlm.nih.gov/pubmed/22158039 http://dx.doi.org/10.1038/onc.2011.569

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