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Anterograde Trafficking of KCa3.1 in Polarized Epithelia Is Rab1- and Rab8-Dependent and Recycling Endosome-Independent

The intermediate conductance, Ca(2+)-activated K(+) channel (KCa3.1) targets to the basolateral (BL) membrane in polarized epithelia where it plays a key role in transepithelial ion transport. However, there are no studies defining the anterograde and retrograde trafficking of KCa3.1 in polarized ep...

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Detalles Bibliográficos
Autores principales: Bertuccio, Claudia A., Lee, Shih-Liang, Wu, Guangyu, Butterworth, Michael B., Hamilton, Kirk L., Devor, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954861/
https://www.ncbi.nlm.nih.gov/pubmed/24632741
http://dx.doi.org/10.1371/journal.pone.0092013