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Ventriculomegaly associated with ependymal gliosis and declines in barrier integrity in the aging human and mouse brain

Age-associated ventriculomegaly is typically attributed to neurodegeneration; however, additional factors might initiate or contribute to progressive ventricular expansion. By directly linking postmortem human MRI sequences with histological features of periventricular tissue, we show that substanti...

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Detalles Bibliográficos
Autores principales: Shook, Brett A, Lennington, Jessica B, Acabchuk, Rebecca L, Halling, Meredith, Sun, Ye, Peters, John, Wu, Qian, Mahajan, Amit, Fellows, Douglas W, Conover, Joanne C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954884/
https://www.ncbi.nlm.nih.gov/pubmed/24341850
http://dx.doi.org/10.1111/acel.12184

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