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Loss of CD11b Exacerbates Murine Complement-Mediated Tubulointerstitial Nephritis
Acute complement activation occurs in the tubulointerstitium (TI) of kidneys transplanted from Crry(−/−)C3(−/−) mice into complement-sufficient wildtype mice, followed by marked inflammatory cell infiltration, tubular damage and interstitial fibrosis. We postulated iC3b-CD11b interactions were criti...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954915/ https://www.ncbi.nlm.nih.gov/pubmed/24632830 http://dx.doi.org/10.1371/journal.pone.0092051 |