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Obesity is associated with higher 4E-BP1 expression in endometrial cancer

PURPOSE: Obesity is associated with risk and prognosis of endometrial cancer (EC), and the mammalian target of rapamycin complex 1 (mTORC1) pathway may play an instrumental role. We sought to explore the associations between cellular proliferation, Akt, and 4E binding protein-1 (4E-BP1) (a downstrea...

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Detalles Bibliográficos
Autores principales: Libby, Emily Falk, Azrad, Maria, Novak, Lea, Vazquez, Ana I, Wilson, Tamara R, Demark-Wahnefried, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955094/
https://www.ncbi.nlm.nih.gov/pubmed/24639918
http://dx.doi.org/10.2147/CBF.S53530