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Production of tropane alkaloids in Hyoscyamus niger (black henbane) hairy roots grown in bubble-column and spray bioreactors
Hairy root cultures of Hyoscyamus niger were cultivated in shake-flasks, a bubble-column bioreactor and a hybrid bubble-column/spray bioreactor and evaluated for alkaloid production. The latter gave the highest anisodamine content (0.67 mg/g dry wt) whereas scopolamine, hyoscyamine and cuscohygrine...
Autores principales: | Jaremicz, Zbigniew, Luczkiewicz, Maria, Kokotkiewicz, Adam, Krolicka, Aleksandra, Sowinski, Pawel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955140/ https://www.ncbi.nlm.nih.gov/pubmed/24322778 http://dx.doi.org/10.1007/s10529-013-1426-9 |
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