Poly(ADP-ribose) polymerase inhibition with HYDAMTIQ reduces allergen-induced asthma-like reaction, bronchial hyper-reactivity and airway remodelling

Activation of poly(ADP-ribose) polymerases (PARPs) is considered a key event in the molecular and cellular processes leading from acute asthma attacks to bronchial hyper-reactivity, leucocyte recruitment, chronic inflammation, airway remodelling and lung damage. The present investigation has been ca...

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Detalles Bibliográficos
Autores principales: Lucarini, Laura, Pini, Alessandro, Gerace, Elisabetta, Pellicciari, Roberto, Masini, Emanuela, Moroni, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955153/
https://www.ncbi.nlm.nih.gov/pubmed/24444146
http://dx.doi.org/10.1111/jcmm.12197

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