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Apelin inhibits the proliferation and migration of rat PASMCs via the activation of PI3K/Akt/mTOR signal and the inhibition of autophagy under hypoxia

Apelin is highly expressed in the lungs, especially in the pulmonary vasculature, but the functional role of apelin under pathological conditions is still undefined. Hypoxic pulmonary hypertension is the most common cause of acute right heart failure, which may involve the remodeling of artery and r...

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Detalles Bibliográficos
Autores principales:	Zhang, Hongyu, Gong, Yongsheng, Wang, Zhouguang, Jiang, Liping, Chen, Ran, Fan, Xiaofang, Zhu, Huanmian, Han, Liping, Li, Xiaokun, Xiao, Jian, Kong, Xiaoxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955159/ https://www.ncbi.nlm.nih.gov/pubmed/24447518 http://dx.doi.org/10.1111/jcmm.12208

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