Halogenated Anesthetics Determination in Urine by SPME/GC/MS and Urine Levels Relationship Evaluation with Surgical Theatres Contamination

In this work, a new sensitive analytical method has been developed and evaluated for the determination of the most commonly used gaseous anesthetics, desflurane, sevoflurane, and this latter's hepatic metabolite hexafluoroisopropanol (HFIP) in the urine. In addition, an evaluation of anesthetic...

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Detalles Bibliográficos
Autores principales: Indelicato, Serena, Bongiorno, David, Indelicato, Sergio, Ceraulo, Leopoldo, Tranchina, Ernesto, Avellone, Giuseppe, Arcadipane, Concetta, Giambartino, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955585/
https://www.ncbi.nlm.nih.gov/pubmed/24719778
http://dx.doi.org/10.1155/2014/753237
Descripción
Sumario:In this work, a new sensitive analytical method has been developed and evaluated for the determination of the most commonly used gaseous anesthetics, desflurane, sevoflurane, and this latter's hepatic metabolite hexafluoroisopropanol (HFIP) in the urine. In addition, an evaluation of anesthetics exposition on the urine levels of a small population of surgical operators has been performed and results are briefly discussed.

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