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Nuclear Nox4-Derived Reactive Oxygen Species in Myelodysplastic Syndromes

A role for intracellular ROS production has been recently implicated in the pathogenesis and progression of a wide variety of neoplasias. ROS sources, such as NAD(P)H oxidase (Nox) complexes, are frequently activated in AML (acute myeloid leukemia) blasts and strongly contribute to their proliferati...

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Detalles Bibliográficos
Autores principales:	Guida, Marianna, Maraldi, Tullia, Beretti, Francesca, Follo, Matilde Y., Manzoli, Lucia, De Pol, Anto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955662/ https://www.ncbi.nlm.nih.gov/pubmed/24719867 http://dx.doi.org/10.1155/2014/456937

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